Motilium (Domperidone)

Domperidone medication information

Domperidone, or Motilium, also known under other brand names, is a medication used primarily to treat and prevent nausea and vomiting, thus acting as a antiemetic drug. The medication has other important effects on body, such as increasing lactation (production of breast milk), and increasing the motility of the gastrointestinal tract (why it has been called Motilium).

The effect of Domperidone is of a psychic nature. The medication works as a dopamine receptor inhibitor, which suppresses the vomiting reactions, and it also stimulates the production of prolactin, responsible for synthesis of breast milk. While the medication has proved efficiency all over the world and patients can buy Motilium (Domperidone) online without prescription in the USA, Canada, the UK, Australia, New Zealand and more than 50 other countries, the Federal Drug Agency of the United States has not yet approved the drug for use in humans. Yet Motilium usage veterinaire is possible in this country.

Currently, Domperidone USA availability is limited to rare cases of prescribed usage, while it is not available over-the-counter in local drug stores, at Walgreens or Walmart. Fortunately, it is possible to order Motilium (Domperidone) medication online with no prescription, and this possibility is used by many people in the United States, who intend to self-medicate vomiting, nausea, or increase the production of breast milk.

Motilium usage

Motilium usage determined by the medical institutions varies from country to country. Generic Domperidone breastfeeding effect, for example, is not commonly taken into consideration by doctors, and the mothers who have problems with lactation have to use it off-label. In this case, they have to buy Motilium (Domperidone) no prescription online pharmacy. In Canada and Australia, the medication is approved for treatment of nausea and vomiting, and is sold over-the-counter without prescription. However, in the United States you can't buy Motilium on your own, and even the prescription of the medication is a rare case.

Other indication for use of Motilium is gastroparesis, which is a delayed emptying of the stomach after eating. In this case, the effect on motility of the gastrointestinal tract makes Domperidone very helpful, stimulating the normal digestion. Domperidone Canada drugs, including Motilium and generic medications, are used for reduction of nausea and vomiting in patients with Parkinson disease, simultaneously increasing the bio-availability of Levodopa medication, primarily used to treat the disease.

There are few other less important indications for use of Motilium, such as functional dyspepsia and others. You can find more information on the web.

Domperidone FDA recommendations

Unfortunately, FDA has not approved the use of Motilium in the United States, except for the rare cases of gastrointestinal issues when it is prescribed by doctors in limited amounts. Therefore, most patients prefer to purchase cheap Motilium (Domperidone) without prescription, or look for a way how to get Domperidone from Canada, where it is legal.

Absence of precaution information makes it important to find out how much Domperidone to induce lactation (how much Domperidone to take to increase milk supply) is needed before you start taking the medication, along with other indications, precautions and contraindications. Here's the list of conditions making the administration of Motilium unwanted:

  • Individual hypersensitivity to the drug's components
  • Therapy using CYP3A4 inhibitors (Triazole, macrolides, grapefruit juice)
  • Liver or kidney diseases
  • Cardiac issues
  • Mechanical gastrointestinal tract disorders
  • Excessive prolactin secretion (lactation)

Generic Motilium (Domperidone) side effects

Usually, patients who do not overdose the medication, do not experience any side effects of the drug. However, individual intolerance, overdose, interactions or other conditions may result in manifestation of such troubles as diarrhea, rash and itching, dry mouth and abdominal cramps. More complex side effects may include hypogonadism (low sexual hormone levels), and related complications, such as menstrual irregularities or erectile dysfunction.

Psychic side effects may include fatigue, insomnia, akathisia, drowsiness and restlessness. Patients may experience depression and parkinsonian symptoms (tremor, rigidity, etc.).

Though Domperidone was believed to be a cause of cardiac complications, such as prolonged QT syndrome and ventricular arrhythmia, recent studies have shown that there is no strong correlation between intake of medium doses of Motilium and these diseases.

How to get Domperidone without prescription

While the medication is available in Motilium Canada OTC and Motilium UK Boots stores, it's not always clear where to buy Domperidone 10mg in the United States. Cost of Motilium (Domperidone) may be too high, if you're looking for a brand drug; however, price of Motilium (Domperidone) generic analogues is much more attractive. You should look for the medication online: most online pharmacies offer Motilium without prescription in the United States. Some patients ask: “Can I Buy Domperidone over the counter in the UK?”. Well, you cannot, unfortunately: the medication has been discontinued since September 2014. Nevertheless, you can order cheap Motilium online, whether you are in the UK, the US, Canada or Australia.


Buy Motilium (Domperidone) Online