Spironolactone, marketed under the brand name of Aldactone and as a generic drug, is a medication that has a wide specter of effects, primarily used to treat hypertension, low blood levels of potassium, to suppress the testosterone (androgen hormone), and with other indications. Spironolactone medication classification defines this drug as a potassium-sparing diuretic. This means that the therapy implies excretion of excessive fluids from body, while keeping the potassium from excretion.
The drug works by inhibiting the mineralocorticoid receptors, inhibiting the androgen receptors and via some other complicated mechanisms. This makes the medication a first-line therapy supplement for women with PCOS, transgender women, hair loss in men and other hormone issues.
Original Spironolactone was first synthesized in 1959, and has quickly become a very popular medication worldwide. World Health Organization has added it on the list of most important medications, essential in basic health system. Today there is a wide specter of generic Aldactone (Spironolactone) medications, that keep the cost of Aldactone (Spironolactone) reasonable and the medication affordable.
There is a wide list of indications that make Spironolactone prescription free for patients. High blood pressure is the most common indication for use of the potassium-sparing diuretic, such as Aldactone. The medication helps to excrete the excessive fluids, thus lowering the blood pressure, but it doesn't result in loss of potassium, so the hypokalemia is avoided. Spironolactone is also useful in treatment of edema, fluid retention and heart failure.
Topical Spironolactone prescription is usually associated with male pattern hair loss, which happens due to high levels of testosterone. In this case, the therapy relies on the androgen receptors blockade effect of the medication. Similarly, Spironolactone is used for treatment of acne in women, which is also associated with elevated levels of testosterone in women. The drug allows removing even the worst cases of cystic acne and normalizing the oil balance in skin.
Transgender women (i.e. men who have chosen to become women) often use Spironolactone in an androgen hormone suppression therapy. It makes them more feminine, inducing the breast development, and suppressing the erectile function. In this case, Aldactone is usually prescribed as a part of combination hormone therapy, along with estrogen.
The drug is often used for children with early puberty and for other indications, such as Spironolactone PCOS therapy, not disclosed in this guide.
The medication is produced in form of oral tablets of Aldactone (Spironolactone) 25 mg, 50 mg, 100 mg. We shall provide a brief instructions regarding the off-label uses of the medication, while general therapy should be administered by a medical specialist. Dosage for off-label uses should be determined individually, though taking into consideration the following recommendations.
Thus, Aldactone dosage for acne is set at initial 50 mg daily, and after several months it can be adjusted to get the best possible effect. Such dosage reduces the risk for most side effects and at the same time has enough therapeutic effect, which is perfect for initial treatment. Your dermatologist can determine how much Spironolactone is in Yaz BC combination therapy giving the best effect. However, patients should know that it takes several weeks for the first improvement in condition to become noticeable.
Aldactone dosage for hair loss depends on individual conditions as well. As a rule, it should start from 25 mg twice a day, and if the patients tolerates the dosage well, it may be increased up to 50 mg or even 100 mg twice a day. However, it is recommended to determine how much Spironolactone for hair loss is required, taking into account the possible complications, so the positive effect outweighs the possible risks.
According to the recent Spironolactone Canada study, the medication can be a cause of various side effects, especially in case of improper dosage, misuse or interactions with other medications. Despite the possibility to buy Aldactone (Spironolactone) online without prescription in Australia, New Zealand, the USA, the UK, Canada and many other developed countries, we recommend to consult a medical specialist to determine the possible contraindications, required dosage and other measures to reduce the risk of side effects.
Typical side effects of the drug are associated with its diuretic effect (hyperkalemia), or suppression of male hormones (breast pain and enlargement, gynecomastia, menstrual disturbances, male fertility). Hypersensitivity to the drug may result in renal failure, anaphylaxis, hepatotoxicity and other rare, though dangerous conditions, which require immediate medical help.
You can order Aldactone (Spironolactone) online with no prescription in most of the developed countries. The benefit of visiting Aldactone (Spironolactone) no prescription online pharmacy is saving your time and money, because Spironolactone price Walmart can differ dramatically from the affordable price on generic Spironolactone for sale without prescription, available online. Nevertheless, despite the possibility to purchase Aldactone (Spironolactone) without prescription, thorough medical examination and consultation is recommended before you start using the drug, because only a medical specialist can determine contraindications and set the proper dosage for the best therapeutic effect.