Tretinoin, marketed under the brand names of Retin-A, Avita and Renova, is a drug commonly used to treat acne vulgaris, acute promyelocytic leukemia and several other diseases. It belongs to retinoid class, particularly a carboxylic acid form of well-known vitamin A. The medication was developed in University of Pennsylvania in the end of 1960's, and then the patent was sold to pharmaceutical company.
As a synthetic form of vitamin A, Tretinoin (Retin-A) has a specter of effects on human body, particularly, it regulates the division and proliferation of different cells, which is the cause of its wide use in medicine. Yet, the exact mechanism of action of the drug is not fully discovered; however, it is widely used in treatment of cancer and acne, which proves its efficiency. The medication has been included on the list of drugs, essential in basic health system, composed by World Heath Organization.
The medication is rather expensive, especially in developed countries, and there is a strict governmental regulation that does not allow citizens order Retin-A (Tretinoin) cream with no prescription in Canada, the UK, the USA, Australia, India and many other countries. Nevertheless, there are certain ways to obtain Tretinoin without prescription, when needed (see below).
The most important use of Tretinoin is the anti-cancer therapy in patients with acute promyelocytic leukemia. In this case, the effect of the medication on human cells induces the differentiation of normal cells from the cancer cells, stopping the proliferation of the last ones, and letting the normal cells to replace them, thus effectively fighting cancer.
The use of Tretinoin is indicated in case the disease does not respond to traditional anthracycline therapy, or the therapy is otherwise unwanted (probably, because of the individual intolerance). It's important to understand that such therapy is possible only under a supervision of medical specialists, and it is not used as maintenance therapy.
One of the most common uses of Tretinoin (its cream form) is treatment of acne vulgaris, a very spread skin problem, most of the teenagers and many adults have. Mechanism of action of Tretinoin (Retin-A) makes epithelial cells divide faster and stick together, which induces the excretion of the blackheads, and prevents their occurrence. People, looking to buy Tretinoin cream no prescription pharmacy, usually have that kind of problems and intend to use the medication to treat acne.
Self-medication with Tretinoin is not recommended, though, if the patient is fully aware of the precautions, contraindications, interactions and adverse effects of the drug, and uses it carefully, the probability of serious problems is quite low. Thousands of people buy no prescription Retin-A (Tretinoin) cream 0.025, 0.05 or 0.1 mg to use it on their own, treating acne vulgaris effectively and safely.
Tretinoin is marked as Pregnancy Category C in the US, and it is believed to be dangerous for pregnant women or breast-feeding mothers. Therefore, any use of Tretinoin (Retin-A) is prohibited if the patient is pregnant, planning pregnancy or breast-feeding.
Other contraindications include hypersensitivity to the drug or its components, vulnerability to the side effects of the drug, high count of white blood cells, and young age. Children should not be allowed to take or use Tretinoin without a doctor's supervision.
The medication has a wide known specter of interactions with other drugs, particularly Ketoconazole, vitamin A, tetracyclines and many other medications. The full list may be found in the instructions of the drug. It is necessary to consult a medical specialist on use of Tretinoin if you are taking any other prescription or non-prescription medicines during the planned course of the drug.
If any of the side effects of Tretinoin manifest in moderate to severe form, or otherwise the patient experiences any unpleasant changes in health condition, it is highly recommended to seek medical advice or help immediately.
Before you buy Retin-A gel or cream online without prescription, it is recommended to familiarize yourself with the list of possible side effects of the drug. If any of these manifest in moderate to severe form, please, contact your doctor immediately for further instructions.
The oral form of Retin-A, used for treatment of acute promyelocytic leukemia, has a number of side effects, including malaise, infections, peripheral edema, benign intracranial hypertension, weight increase, anorexia, myalgia, respiratory tract disorders, dyspnea, pneumonia, respiratory insufficiency, feeling of fullness in ears, diarrhea, constipation, dyspepsia, arrhythmia, flushing, hypotension, dizziness, depression, insomnia, anxiety, and many others.
Fortunately, Retin-A cream or gel for on-skin application causes much less adverse effects. Possible complications include redness, skin irritation, blistering and swelling. Skin resistance to ultraviolet radiation may be lowered.
Price of Retin-A is not very attractive, if you want to buy the brand drug with prescription. However, there is a possibility to buy Retin-A micro pump without prescription, if you are willing to cut the unnecessary expenses. Treatment of acne vulgaris doesn't really require medical help or prescription, if the patient is using it reasonably and according to the instructions, with precautions.
If you want to know, how much does Tretinoin cream cost online, you should look for an online pharmacy, which helps to purchase Retin-A (Tretinoin) micro online without prescription. You should only order the drug from reliable suppliers, especially if you're looking for a generic analogue of Retin-A, which is much cheaper and nearly as effective as the original Tretinoin. If you have any doubt in that, you can consult your doctor, which is recommended to all who are intended to use the medication for the first time.